Biphasic Epithelial Predominant Synovial Sarcoma Presenting as Painful Thigh Mass

Authors

  • Elham Mirzaian Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Sahar Montazeri Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran
Abstract:

Synovial sarcomas are soft tissue neoplasms mostly located in the lower extremities of young adults. A case of synovial sarcoma of the thigh in a 35-year-old male with the predominant epithelial component is reported. Microscopically the tumor showed variable-sized well-differentiated glands lined by the cuboidal cells with small foci of spindle cell component between glandular structures. Immunohistochemically glandular components showed positivity for the pan CK and EMA while CD99 and TLE1 were positive in both glandular and spindle cell components. This type of synovial sarcoma could be indistinguishable from metastatic adenocarcinoma and malignant adnexal tumor, thus, immunohistochemistry and molecular studies play an essential role in the exact diagnosis of this type of tumor.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Epithelial predominant synovial sarcoma presenting as chronic non-healing ulcer of foot: A rare presentation

Synovial sarcoma is defined as a mesenchymal spindle cell tumour which displays variable epithelial differentiation including glandular formation and has a specific chromosomal translocation [1]. It is an aggressive and rare neoplasm which is histologically classified into two subtypes: monophasic and biphasic. Epithelial predominant synovial sarcoma can mimic epithelial neoplasms and is freque...

full text

Granulocytic Sarcoma Presenting as Subconjunctival Mass

  Chloroma or granulocytic sarcoma (GS) is a malignant neoplasm of myeloid lineage that occur in a variety of anatomic sites other than the bone marrow including soft tissue, bone, lymph node, nasal fossa, skin and sometime in the orbit. In the subconjunctiva it is rarely reported. A 4-year-old girl with a history of treated acute myelogenous leukemia was referred to Farabi Eye Hospital, Tehra...

full text

Primary Synovial Sarcoma Presenting as a Huge Mass: A Report of a Rare Case and Review of Literature

Primary synovial sarcoma of mediastinum is very rare among soft tissue sarcomas. Only a few cases have been reportedin the literatures. The best treatment is still unclear, but, surgical resection is the main therapy. In this article we reporta case of a 20*20 cm (2000gr) primary giant mediastinal synovial sarcoma in a 42 year-old man. We performed radicalexcision of the tumor...

full text

Primary intrathoracic biphasic synovial sarcoma.

Synovial sarcomas are most frequently observed in the extremities. Although synovial sarcomas are the third most common histological type of soft-tissue sarcomas of the extremities, primary mediastinal synovial sarcoma is extremely rare. Monophasic synovial sarcoma is the most commonly observed subtype. whereas the biphasic subtype is less common. We present our case which was diagnosed as biph...

full text

Retroperitoneal synovial sarcoma presenting as paraneoplastic hypoglycaemia

Synovial sarcoma is a well-recognized malignant mesenchymal neoplasm. Primary retroperitoneal synovial sarcoma is extremely rare and has poor prognosis. There are sparse reports in the literature on the secretory synovial sarcomas. In this report, we present the case of a patient with retroperitoneal synovial sarcoma who presented with recurrent attacks of hypoglycaemia.

full text

granulocytic sarcoma presenting as subconjunctival mass

chloroma or granulocytic sarcoma (gs) is a malignant neoplasm of myeloid lineage that occur in a variety of anatomic sites other than the bone marrow including soft tissue, bone, lymph node, nasal fossa, skin and sometime in the orbit. in the subconjunctiva it is rarely reported. a 4-year-old girl with a history of treated acute myelogenous leukemia was referred to farabi eye hospital, tehran, ...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 14  issue 3

pages  261- 264

publication date 2019-08-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023